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Mental and Physical Health Information
Macrocytosis
Macrocytosis
| Macrocytosis Classification and external resources | |
| ICD-10 | D75.8 |
|---|---|
| ICD-9 | 289.89 |
| DiseasesDB | 7688 |
| eMedicine | med/1381 |
Macrocytosis is the enlargement of red blood cells with near-constant haemoglobin concentration, and is defined by a mean corpuscular volume (MCV) of greater than 100 femtolitres (the precise criterion varies between laboratories).
Causes
Most commonly (especially when the increase in size is mild, and just above normal range) the etiology is bone marrow dysplasia primary to alcohol abuse. Other causes may include:
- Megaloblastosis (Vitamin B12 or folate deficiency; or DNA synthesis-inbiting drugs)
- hypothyroidism
- reticulocytosis (commonly from hemolysis or a recent history of blood loss).
- liver disease
- myeloproliferative disease
Even more about Macrocytosis
Macrocytosis
Macrocytosis is a term used to describe erythrocytes that are larger than normal, typically reported as mean cell volume
eMedicine - Macrocytosis : Article by Wendy Brick
Macrocytosis is the enlargement of red blood cells with near-constant haemoglobin concentration, and is defined by a mean corpuscular volume (MCV) of greater than 100 femtolitres ...
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