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Sodium Valproate


Sodium valproate
Systematic (IUPAC) name
sodium 2-propylpentanoate
Identifiers
CAS number	1069-66-5
ATC code	N03AG01
PubChem	14047
Chemical data
Formula	C₈H₁₅NaO₂
Mol. mass	166.20 g/mol
Pharmacokinetic data
Bioavailability	?
Protein binding	90–95%
Metabolism	75% by CYP enzymes
Half life	9–18 hours
Excretion	20% excreted as glucuronide
Therapeutic considerations
Pregnancy cat.	D(AU) D(US)
Legal status	POM(UK) ℞-only(US)
Routes	Oral, i.v.

Sodium valproate (INN) or valproate sodium (USAN) is the sodium salt of valproic acid and is an anticonvulsant used in the treatment of epilepsy and bipolar disorder, as well as other psychiatric conditions requiring the administration of a mood stabilizer. The intravenous formulations are used when oral administration is not possible.

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Sodium valproate or valproate sodium is the sodium salt of valproic acid and is an anticonvulsant used in the treatment of epilepsy and bipolar disorder, as well as other ...

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